What should I discuss with my healthcare provider before using sumatriptan? In the controlled clinical trials assessing the efficacy of Imitrex Injection as a treatment for cluster headache Studies 4 and 5 no new significant adverse reactions were detected that had not already been identified in trials of IMITREX in patients with migraine. In a trial of 14 healthy females, pretreatment with an MAO-A inhibitor decreased the clearance of subcutaneous sumatriptan, resulting in a 2-fold increase in the area under the sumatriptan plasma concentration-time curve AUC corresponding to a 40% increase in elimination half-life. osef.info disulfiram
Neurological: Infrequent were mental confusion, euphoria, agitation, relaxation, chills, sensation of lightness, tremor, shivering, disturbances of taste, prickling sensations, paresthesia, stinging sensations, facial pain, photophobia, and lacrimation. Know the medicines you take. To recall numbers, group them and then relate them to a date or story. IMITREX Injection, call your doctor immediately. AMERGE, IMITREX, IMITREX STATdose System, and IMITREX STATdose Pen are registered trademarks of the GSK group of companies. The other brands listed are trademarks of their respective owners and are not trademarks of the GSK group of companies. The makers of these brands are not affiliated with and do not endorse the GSK group of companies or its products.
How should I take IMITREX? IMITREX and certain other medicines can affect each other, causing serious side effects. Overall, the frequency of adverse reactions reported in the trials of cluster headache was generally lower than in the migraine trials. Exceptions include reports of paresthesia 5% Imitrex Injection, 0% placebo nausea and vomiting 4% Imitrex Injection, 0% placebo and bronchospasm 1% Imitrex Injection, 0% placebo.
Associated symptoms such as nausea, photophobia, and phonophobia were also assessed. IMITREX Injection should not be given to patients with history, symptoms, or signs of ischemic cardiac, cerebrovascular, or peripheral vascular syndromes. In addition, patients with other significant underlying cardiovascular diseases should not receive IMITREX Injection. The sum of the percentages cited is greater than 100% because patients may experience more than 1 type of adverse event. Only events that occurred at a frequency of 1% or more in groups treated with IMITREX Injection and were at least as frequent in the placebo groups are included. piroxicam
The risk of heart disease, liver disease, and high blood pressure increases with age. The manufacturer does not recommend the use of sumatriptan in the elderly since they may be more sensitive to the side effects, including an increase in blood pressure. Franceschini R, Cataldi A, Garibaldi A, Cianciosi P, Scordamaglia A, Barreca T, Rolandi E "The effects of sumatriptan on pituitary secretion in man. Hepatic Impairment: The effect of hepatic disease on the pharmacokinetics of subcutaneously and orally administered sumatriptan has been evaluated. There were no statistically significant differences in the pharmacokinetics of subcutaneously administered sumatriptan in hepatically impaired patients compared to healthy controls. However, the liver plays an important role in the presystemic clearance of orally administered sumatriptan. Accordingly, the bioavailability of sumatriptan following oral administration may be markedly increased in patients with liver disease. If you are taking this product on a regular schedule and miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Medicines can help you feel better. But they can also be dangerous, especially if you don't take them the right way. Be safe with medicines. Read and follow all instructions on the label. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant while using Imitrex Injection. It is unknown if Imitrex Injection will harm a fetus. Your name may need to be listed on a sumatriptan pregnancy registry when you start using Imitrex Injection. Imitrex Injection can pass into breast milk and may harm a nursing baby. Do not breastfeed within 12 hours after using Imitrex Injection. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby. Before having surgery, tell your doctor or dentist about all the products you use including prescription drugs, nonprescription drugs, and herbal products. The figure uses Kaplan-Meier product limit Survivorship Plot. Some sumatriptan side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear.
What are the possible side effects of IMITREX? Sumatriptan is injected under the skin. You may be shown how to use injections at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of used needles and syringes. Alcohol: Alcohol consumed 30 minutes prior to sumatriptan ingestion had no effect on the pharmacokinetics of sumatriptan. This information should not be used to decide whether or not to take Imitrex spray or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Imitrex spray. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Imitrex spray. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Imitrex spray. Some medical conditions may interact with Imitrex tablets. Sumatriptan does not prevent future migraines or lessen how often you get migraine attacks. It is best to take a dose of Imitrex tablets as soon as you notice symptoms of a migraine attack. Inform patients that Imitrex Injection may cause serious cardiovascular side effects such as myocardial infarction or stroke. Although serious cardiovascular events can occur without warning symptoms, patients should be alert for the signs and symptoms of chest pain, shortness of breath, irregular heartbeat, significant rise in blood pressure, weakness, and slurring of speech, and should ask for medical advice if any indicative sign or symptoms are observed. You should give an injection as soon as the symptoms of your headache start, but it may be given at any time during a migraine or cluster headache attack. Use of this medicine for 10 or more days per month may exacerbate headaches; use a headache diary to record how often you have a headache and when you take this medicine. Pediatric Use: Safety and effectiveness of IMITREX Injection in pediatric patients under 18 years of age have not been established; therefore, IMITREX Injection is not recommended for use in patients under 18 years of age. In patients who experience symptoms or signs suggestive of non-coronary vasospasm reaction following the use of any 5-HT 1 agonist, rule out a vasospastic reaction before receiving additional Imitrex Injections. proventil
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. This does not prevent future or lessen how often you get attacks. My doctor tells me my body couldn't handle the return to normal food, and reacted with the diarrhea and subsequent headaches. Sumatriptan is used to treat migraine headaches. Sumatriptan will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks. Burning, tingling, dryness or pain in the nose nasal spray. Oral administration of sumatriptan to rats prior to and throughout gestation resulted in embryofetal toxicity decreased body weight, decreased ossification, increased incidence of skeletal abnormalities. In some cases, your doctor may prescribe stronger medicine if over-the-counter drugs don't stop your headaches. Serotonin syndrome is a possibly fatal syndrome that can be caused by Imitrex spray. Your risk may be greater if you take Imitrex spray with certain other medicines eg, SSRIs, SNRIs. Symptoms may include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and nausea, vomiting, or diarrhea. Contact your doctor at once if you have any of these symptoms. Musculoskeletal: Infrequent were various joint disturbances pain, stiffness, swelling, ache. Rare were muscle stiffness, need to flex calf muscles, backache, muscle tiredness, and swelling of the extremities.
Eye: Ischemic optic neuropathy, retinal artery occlusion, retinal vein thrombosis, loss of vision. Case to reset the white Priming before the next use. IMITREX STATdose System NDC 0173-0739-02. Autoinjector Pen: Each pack contains a Patient Information and Instructions for Use leaflet. Sumatriptan is not approved for use by anyone younger than 18 years old. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Usually the benefits of the medicine are more important than any minor side effects. Try these drugs first. generic risperdal online buy
Ergot-containing drugs have been reported to cause prolonged vasospastic reactions. Because these effects may be additive, use of ergotamine-containing or ergot-type medications like dihydroergotamine or methysergide and Imitrex Injection within 24 hours of each other is contraindicated. There is no evidence that establishes that sumatriptan is a human teratogen; however, there are no adequate and well-controlled studies in pregnant women. IMITREX Injection should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Each tablet also contains the inactive ingredients croscarmellose sodium, dibasic calcium phosphate, magnesium stearate, microcrystalline cellulose, and sodium bicarbonate. Each 100-mg tablet also contains hypromellose, iron oxide, titanium dioxide, and triacetin. Hepatic: Elevated liver function tests. Cerebral hemorrhage, subarachnoid hemorrhage, and stroke have occurred with 5-HT1 treatment; some have resulted in fatalities. One case of sumatriptan-induced cortical stroke has been reported in a patient with sagittal sinus thrombosis. In some cases, it appears possible that the cerebrovascular events were primary, and the 5-HT1 agonist administered in the belief that presenting symptoms were due to migraine when they were not. Patients with migraine may also be at an increased risk of certain cerebrovascular events such as stroke, hemorrhage, and transient ischemic attacks. After using an injection: If your headache does not completely go away after the injection, call your doctor before using a second sumatriptan injection. If your headache goes away and then comes back, you may use a second injection if it has been at least one 1 hour since your first injection. Do not use more than two 2 injections in 24 hours. If your symptoms do not improve, contact your doctor before using any more injections. Imitrex may cause serious side effects. See “What is the most important information I should know about Imitrex? Incidence in Controlled Trials of Cluster Headache: In the controlled clinical trials assessing sumatriptan's efficacy as a treatment for cluster headache, no new significant adverse events associated with the use of sumatriptan were detected that had not already been identified in association with the drug's use in migraine. Triptans narrow constrict vessels in the and relieve swelling. Triptans have other properties that may help treat symptoms.
Side Effects List Sumatriptan-Naproxen Tablet side effects by likelihood and severity. Treatment of migraine attacks with sumatriptan. the subcutaneous sumatriptan international study group. Take one sumatriptan tablet whole with a full glass of water. Do not split the tablet. This list is not complete. Other drugs may interact with sumatriptan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. This medication may also be used as a backup for sumatriptan injection. If your symptoms are only partly relieved or your headache comes back, you may take a dose of sumatriptan by mouth at least two hours after the injection, up to a maximum of 100 milligrams in a 24-hour period. Willett F, Curzen N, Adams J, Armitage M "Coronary vasospasm induced by subcutaneous sumatriptan. Since the injection is intended to be given subcutaneously, intramuscular or intravascular delivery should be avoided. Patients should be directed to use injection sites with an adequate skin and subcutaneous thickness to accommodate the length of the needle. IMITREX STATdose Pen, 2 prefilled single-dose syringe cartridges, and 1 carrying case NDC 0173-0739-00. Eye: Accommodation disorders, blindness and low vision, conjunctivitis, disorders of sclera, external ocular muscle disorders, eye edema and swelling, eye hemorrhage, eye itching, eye pain, keratitis, mydriasis, and visual disturbances. Meniere disease; nasal inflammation; otalgia; sensitivity to noise; sinusitis; tinnitus; and upper respiratory inflammation. Injection when you start taking it and at regular checkups. Avoid for at least 12 hours after using sumatriptan. Consult your doctor before -feeding. You may find that combining a triptan with a nonprescription medicine such as or helps to stop your headaches better. Talk to your doctor about this option if triptans alone aren't helping enough. Burning, pain, or redness where the shot was given. minomycin at discount
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Product Information. Imitrex sumatriptan. This drug may make you dizzy or drowsy. not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid beverages. You will need to check your blood pressure often. Talk with your doctor. order clopidogrel store
Ottervanger JP, Vanwitsen TB, Valkenburg HA, Grobbee DE, Stricker BHC "Adverse reactions attributed to sumatriptan - a postmarketing study in general practice. Certain conditions can increase your risk for heart problems. Tell your doctor if you have any of these conditions, including: high blood pressure, high cholesterol, diabetes, family history of heart disease, overweight, smoker, postmenopausal women age more than 40 years men. Heart attack and other heart problems. Heart problems may lead to death.
IMITREX is not used to treat other types of headaches such as hemiplegic that make you unable to move on one side of your body or basilar rare form of migraine with aura migraines. Endocrine and Metabolic: Infrequent was thirst. Review all your prescription and nonprescription and dosages with your doctor or pharmacist. Many medicines, by themselves or in combination with other medicines, can cause mental confusion. Also, confusion may occur when medicines interact in your body. If you see several doctors, make sure that they all know what other medicines you are taking. Have all of your filled at the same pharmacy. Ask your doctor or pharmacist whether the combination of your medicines could cause problems. how much is generic hyzaar without insurance
Because it sure FEELS serious! Serious and sometimes fatal brain blood vessel problems like stroke have rarely happened with Imitrex spray. Contact your doctor at once if you have confusion, one-sided weakness, or speech or vision changes. You should not use this medicine if you have uncontrolled high blood pressure, heart problems, certain heart rhythm disorders, a history of heart attack or stroke, or circulation problems that cause a lack of blood supply within the body. If you do not get any relief after your first tablet, do not take a second tablet without first talking with your healthcare provider.